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Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors.
Kosti, Paris; Opzoomer, James W; Larios-Martinez, Karen I; Henley-Smith, Rhonda; Scudamore, Cheryl L; Okesola, Mary; Taher, Mustafa Y M; Davies, David M; Muliaditan, Tamara; Larcombe-Young, Daniel; Woodman, Natalie; Gillett, Cheryl E; Thavaraj, Selvam; Maher, John; Arnold, James N.
Afiliação
  • Kosti P; School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Campus, London SE1 1UL, UK.
  • Opzoomer JW; School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Campus, London SE1 1UL, UK.
  • Larios-Martinez KI; School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Campus, London SE1 1UL, UK.
  • Henley-Smith R; King's Health Partners Head and Neck Cancer Biobank, Guy's and St Thomas' NHS Foundation Trust, London SE1 9RT, UK.
  • Scudamore CL; ExePathology, Exmouth EX81TN, UK.
  • Okesola M; School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Campus, London SE1 1UL, UK.
  • Taher MYM; School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Campus, London SE1 1UL, UK.
  • Davies DM; Department of Laboratory Medicine, Taibah University, Medina 42353, Saudi Arabia.
  • Muliaditan T; School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Campus, London SE1 1UL, UK.
  • Larcombe-Young D; School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Campus, London SE1 1UL, UK.
  • Woodman N; School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Campus, London SE1 1UL, UK.
  • Gillett CE; School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Campus, London SE1 1UL, UK.
  • Thavaraj S; School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Campus, London SE1 1UL, UK.
  • Maher J; Centre for Oral, Clinical and Translational Sciences, King's College London, Guy's Campus, London SE1 9RT, UK.
  • Arnold JN; School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Campus, London SE1 1UL, UK.
Cell Rep Med ; 2(4): 100227, 2021 04 20.
Article em En | MEDLINE | ID: mdl-33948568

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T / Imunoterapia Adotiva / Microambiente Tumoral / Receptores de Antígenos Quiméricos / Hipóxia Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T / Imunoterapia Adotiva / Microambiente Tumoral / Receptores de Antígenos Quiméricos / Hipóxia Idioma: En Ano de publicação: 2021 Tipo de documento: Article