Diagnostic criteria for apathy in neurocognitive disorders.
Alzheimers Dement
; 17(12): 1892-1904, 2021 12.
Article
em En
| MEDLINE
| ID: mdl-33949763
ABSTRACT
INTRODUCTION:
Apathy is common in neurocognitive disorders (NCD) but NCD-specific diagnostic criteria are needed.METHODS:
The International Society for CNS Clinical Trials Methodology Apathy Work Group convened an expert group and sought input from academia, health-care, industry, and regulatory bodies. A modified Delphi methodology was followed, and included an extensive literature review, two surveys, and two meetings at international conferences, culminating in a consensus meeting in 2019.RESULTS:
The final criteria reached consensus with more than 80% agreement on all parts and included limited to people with NCD; symptoms persistent or frequently recurrent over at least 4 weeks, a change from the patient's usual behavior, and including one of the following diminished initiative, diminished interest, or diminished emotional expression/responsiveness; causing significant functional impairment and not exclusively explained by other etiologies.DISCUSSION:
These criteria provide a framework for defining apathy as a unique clinical construct in NCD for diagnosis and further research.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Técnica Delphi
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Transtornos Neurocognitivos
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Consenso
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Prova Pericial
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Apatia
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article