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P38 mitogen activated protein kinase inhibitor improves platelet in vitro parameters and in vivo survival in a SCID mouse model of transfusion for platelets stored at cold or temperature cycled conditions for 14 days.
Skripchenko, Andrey; Gelderman, Monique P; Vostal, Jaroslav G.
Afiliação
  • Skripchenko A; Division of Blood Components and Devices, Laboratory of Cellular Hematology, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
  • Gelderman MP; Division of Blood Components and Devices, Laboratory of Cellular Hematology, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
  • Vostal JG; Division of Blood Components and Devices, Laboratory of Cellular Hematology, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.
PLoS One ; 16(5): e0250120, 2021.
Article em En | MEDLINE | ID: mdl-33974660

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Agregação Plaquetária / Transfusão de Plaquetas / Proteínas Quinases p38 Ativadas por Mitógeno / Inibidores de Proteínas Quinases Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Agregação Plaquetária / Transfusão de Plaquetas / Proteínas Quinases p38 Ativadas por Mitógeno / Inibidores de Proteínas Quinases Idioma: En Ano de publicação: 2021 Tipo de documento: Article