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An aged immune system drives senescence and ageing of solid organs.
Yousefzadeh, Matthew J; Flores, Rafael R; Zhu, Yi; Schmiechen, Zoe C; Brooks, Robert W; Trussoni, Christy E; Cui, Yuxiang; Angelini, Luise; Lee, Kyoo-A; McGowan, Sara J; Burrack, Adam L; Wang, Dong; Dong, Qing; Lu, Aiping; Sano, Tokio; O'Kelly, Ryan D; McGuckian, Collin A; Kato, Jonathan I; Bank, Michael P; Wade, Erin A; Pillai, Smitha P S; Klug, Jenna; Ladiges, Warren C; Burd, Christin E; Lewis, Sara E; LaRusso, Nicholas F; Vo, Nam V; Wang, Yinsheng; Kelley, Eric E; Huard, Johnny; Stromnes, Ingunn M; Robbins, Paul D; Niedernhofer, Laura J.
Afiliação
  • Yousefzadeh MJ; Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, MN, USA.
  • Flores RR; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA.
  • Zhu Y; Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, MN, USA.
  • Schmiechen ZC; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA.
  • Brooks RW; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.
  • Trussoni CE; Center for Immunology, University of Minnesota Medical School, Minneapolis, MN, USA.
  • Cui Y; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, USA.
  • Angelini L; Division of Gastroenterology, Center for Cell Signaling in Gastroenterology, Mayo Clinic, Rochester, MN, USA.
  • Lee KA; Department of Chemistry, University of California Riverside, Riverside, CA, USA.
  • McGowan SJ; Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, MN, USA.
  • Burrack AL; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA.
  • Wang D; Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, MN, USA.
  • Dong Q; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA.
  • Lu A; Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, MN, USA.
  • Sano T; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA.
  • O'Kelly RD; Center for Immunology, University of Minnesota Medical School, Minneapolis, MN, USA.
  • McGuckian CA; Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
  • Kato JI; Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
  • Bank MP; Department of Orthopedic Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Wade EA; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, USA.
  • Pillai SPS; Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, MN, USA.
  • Klug J; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA.
  • Ladiges WC; Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, MN, USA.
  • Burd CE; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA.
  • Lewis SE; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, USA.
  • LaRusso NF; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, USA.
  • Vo NV; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, USA.
  • Wang Y; Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Kelley EE; Department of Comparative Medicine, University of Washington, Seattle, WA, USA.
  • Huard J; Department of Comparative Medicine, University of Washington, Seattle, WA, USA.
  • Stromnes IM; Departments of Molecular Genetics and Cancer Biology and Genetics, The Ohio State University, Columbus, OH, USA.
  • Robbins PD; Department of Physiology & Pharmacology, West Virginia University, Morgantown, WV, USA.
  • Niedernhofer LJ; Division of Gastroenterology, Center for Cell Signaling in Gastroenterology, Mayo Clinic, Rochester, MN, USA.
Nature ; 594(7861): 100-105, 2021 06.
Article em En | MEDLINE | ID: mdl-33981041
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Especificidade de Órgãos / Envelhecimento / Imunossenescência / Sistema Imunitário Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Especificidade de Órgãos / Envelhecimento / Imunossenescência / Sistema Imunitário Idioma: En Ano de publicação: 2021 Tipo de documento: Article