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Impact of technical innovations in EMR in the treatment of large nonpedunculated polyps involving the ileocecal valve (with video).
Vosko, Sergei; Gupta, Sunil; Shahidi, Neal; van Hattem, W Arnout; Zahid, Simmi; McKay, Owen; Whitfield, Anthony; Sidhu, Mayenaaz; Tate, David J; Lee, Eric Y T; Byth, Karen; Williams, Stephen J; Burgess, Nicholas; Bourke, Michael J.
Afiliação
  • Vosko S; Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia.
  • Gupta S; Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia; Westmead Clinical School, University of Sydney, Sydney, New South Wales, Australia.
  • Shahidi N; Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia; Westmead Clinical School, University of Sydney, Sydney, New South Wales, Australia; Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • van Hattem WA; Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia.
  • Zahid S; Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia.
  • McKay O; Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia.
  • Whitfield A; Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia; Westmead Clinical School, University of Sydney, Sydney, New South Wales, Australia.
  • Sidhu M; Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia; Westmead Clinical School, University of Sydney, Sydney, New South Wales, Australia.
  • Tate DJ; University Hospital Gent, Gent, Belgium.
  • Lee EYT; Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia; Westmead Clinical School, University of Sydney, Sydney, New South Wales, Australia.
  • Byth K; National Health and Medical Research Council Clinical Trials Centre, University of Sydney, Sydney, New South Wales, Australia; WSLHD Research and Education Network, Westmead Hospital, Sydney, New South Wales, Australia.
  • Williams SJ; Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia; Westmead Clinical School, University of Sydney, Sydney, New South Wales, Australia.
  • Burgess N; Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia; Westmead Clinical School, University of Sydney, Sydney, New South Wales, Australia.
  • Bourke MJ; Department of Gastroenterology and Hepatology, Westmead Hospital, Sydney, New South Wales, Australia; Westmead Clinical School, University of Sydney, Sydney, New South Wales, Australia.
Gastrointest Endosc ; 94(5): 959-968.e2, 2021 11.
Article em En | MEDLINE | ID: mdl-33989645
ABSTRACT
BACKGROUND AND

AIMS:

The endoscopic management of large nonpedunculated colorectal polyps involving the ileocecal valve (ICV-LNPCPs) remains challenging because of its unique anatomic features, with long-term outcomes inferior to LNPCPs not involving the ICV. We sought to evaluate the impact of technical innovations and advances in the EMR of ICV-LNPCPs.

METHODS:

The performance of EMR for ICV-LNPCPs was retrospectively evaluated in a prospective observational cohort of LNPCPs ≥20 mm. Efficacy was measured by clinical success (removal of all polypoid tissue during index EMR and avoidance of surgery) and recurrence at first surveillance colonoscopy. Accounting for the adoption of technical innovations, comparisons were made between an historical cohort (September 2008 to April 2016) and contemporary cohort (May 2016 to October 2020). Safety was evaluated by documenting the frequencies of intraprocedural bleeding, delayed bleeding, deep mural injury, and delayed perforation.

RESULTS:

Between September 2008 to October 2020, 142 ICV-LNPCPs were referred for EMR. Median ICV-LNPCP size was 35 mm (interquartile range, 25-50 mm). When comparing the contemporary (n = 66) and historical cohorts (n = 76) of ICV-LNPCPs, there were significant differences in clinical success (93.9% vs 77.6%, P = .006) and recurrence (4.6% vs 21.0%, P = .019).

CONCLUSIONS:

With technical advances, ICV-LNPCPs can be effectively and safely managed by EMR, independent of lesion complexity. Most patients experience excellent outcomes and avoid surgery.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pólipos do Colo / Ressecção Endoscópica de Mucosa / Valva Ileocecal Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pólipos do Colo / Ressecção Endoscópica de Mucosa / Valva Ileocecal Idioma: En Ano de publicação: 2021 Tipo de documento: Article