Crocetin and Its Glycoside Crocin, Two Bioactive Constituents From <i>Crocus sativus</i> L. (Saffron), Differentially Inhibit Angiogenesis by Inhibiting Endothelial Cytoskeleton Organization and Cell Migration Through VEGFR2/SRC/FAK and VEGFR2/MEK/ERK Signaling Pathways.

Zhao, Chen; Kam, Hio-Tong; Chen, Yan; Gong, Guiyi; Hoi, Maggie Pui-Man; Skalicka-Wozniak, Krystyna; Dias, Alberto Carlos Pires; Lee, Simon Ming-Yuen

Crocetin and Its Glycoside Crocin, Two Bioactive Constituents From Crocus sativus L. (Saffron), Differentially Inhibit Angiogenesis by Inhibiting Endothelial Cytoskeleton Organization and Cell Migration Through VEGFR2/SRC/FAK and VEGFR2/MEK/ERK Signaling Pathways.

Zhao, Chen; Kam, Hio-Tong; Chen, Yan; Gong, Guiyi; Hoi, Maggie Pui-Man; Skalicka-Wozniak, Krystyna; Dias, Alberto Carlos Pires; Lee, Simon Ming-Yuen.

Afiliação

Zhao C; State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macao, China.
Kam HT; State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macao, China.
Chen Y; State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macao, China.
Gong G; State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macao, China.
Hoi MP; State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macao, China.
Skalicka-Wozniak K; Independent Laboratory of Natural Products Chemistry, Department of Pharmacognosy, Medical University of Lublin, Lublin, Poland.
Dias ACP; Centre for the Research and Technology of Agro-Environment and Biological Sciences (CITAB-UM), AgroBioPlant Group, Department of Biology, University of Minho, Braga, Portugal.
Lee SM; State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macao, China.

Front Pharmacol ; 12: 675359, 2021.

Article em En | MEDLINE | ID: mdl-33995106