A Dual pH-Responsive DOX-Encapsulated Liposome Combined with Glucose Administration Enhanced Therapeutic Efficacy of Chemotherapy for Cancer.

Zhai, Luoping; Luo, Chuangwei; Gao, Hannan; Du, Shuaifan; Shi, Jiyun; Wang, Fan

Zhai, Luoping; Luo, Chuangwei; Gao, Hannan; Du, Shuaifan; Shi, Jiyun; Wang, Fan.

Afiliação

Zhai L; Medical Isotopes Research Center and Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, 100191, People's Republic of China.
Luo C; Medical Isotopes Research Center and Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, 100191, People's Republic of China.
Gao H; Medical Isotopes Research Center and Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, 100191, People's Republic of China.
Du S; Medical Isotopes Research Center and Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, 100191, People's Republic of China.
Shi J; Key Laboratory of Protein and Peptide Pharmaceuticals, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Academy of Sciences, Beijing, 100101, People's Republic of China.
Wang F; Medical Isotopes Research Center and Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, 100191, People's Republic of China.

Int J Nanomedicine ; 16: 3185-3199, 2021.

Article em En | MEDLINE | ID: mdl-34007173

Assuntos

Doxorrubicina/uso terapêutico; Sistemas de Liberação de Medicamentos; Glucose/administração & dosagem; Neoplasias/tratamento farmacológico; Animais; Antineoplásicos/farmacologia; Antineoplásicos/uso terapêutico; Morte Celular/efeitos dos fármacos; Linhagem Celular Tumoral; Doxorrubicina/farmacologia; Liberação Controlada de Fármacos; Endocitose/efeitos dos fármacos; Humanos; Concentração de Íons de Hidrogênio; Lipossomos; Camundongos Endogâmicos BALB C; Neoplasias/patologia; Imagem Óptica; Tamanho da Partícula; Fosfatidiletanolaminas/química

Palavras-chave

DOX; dual pH-responsive; liposomes; pH (low) insertion peptide; tumor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doxorrubicina / Sistemas de Liberação de Medicamentos / Glucose / Neoplasias Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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