IS THERE CORRELATION BETWEEN HUMAN PAPILLOMAVIRUS (HPV) AND ESOPHAGEAL EPIDERMOID CARCINOMA?
Arq Bras Cir Dig
; 34(1): e1528, 2021 May 14.
Article
em En, Pt
| MEDLINE
| ID: mdl-34008702
ABSTRACT
BACKGROUND:
Currently, persistent human papillomavirus (HPV) infection has been related in some geographic regions as a risk factor for esophageal squamous cell carcinoma. It results in the immunoexpression of the p16 protein, which has been used as marker of the oncogenic lineage by this etiological agent.AIM:
To correlate epidemiological aspects of esophageal squamous cell carcinoma with the prevalence of HPV infection.METHODS:
Fifty-eight cases were analyzed and submitted to histopathological and immunohistochemical analysis by p16.RESULTS:
Of the 58 cases evaluated, 40 were men and 18 women, with a mean age of 63.2 years. p16 immunoexpression was positive in 46.55%.CONCLUSION:
The prevalence of HPV infection is high in esophageal squamous cell carcinoma presenting in almost half of the cases (46.55%), without gender differentiation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Esofágicas
/
Carcinoma de Células Escamosas
/
Infecções por Papillomavirus
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Alphapapillomavirus
/
Carcinoma de Células Escamosas do Esôfago
Idioma:
En
/
Pt
Ano de publicação:
2021
Tipo de documento:
Article