Neurological manifestations of hepatitis E virus infection: An overview.
World J Gastroenterol
; 27(18): 2090-2104, 2021 May 14.
Article
em En
| MEDLINE
| ID: mdl-34025066
ABSTRACT
Hepatitis E virus (HEV) is an important cause of repeated waterborne outbreaks of acute hepatitis. Recently, several extrahepatic manifestations (EHMs) have been described in patients with HEV infection. Of these, neurological disorders are the most common EHM associated with HEV. The involvement of both the peripheral nervous system and central nervous system can occur together or in isolation. Patients can present with normal liver function tests, which can often be misleading for physicians. There is a paucity of data on HEV-related neurological manifestations; and these data are mostly described as case reports and case series. In this review, we analyzed data of 163 reported cases of HEV-related neurological disorders. The mechanisms of pathogenesis, clinico-demographic profile, and outcomes of the HEV-related neurological disorders are described in this article. Nerve root and plexus disorder were found to be the most commonly reported disease, followed by meningoencephalitis.
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Base de dados:
MEDLINE
Assunto principal:
Neurite do Plexo Braquial
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Vírus da Hepatite E
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Hepatite E
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Doenças do Sistema Nervoso
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article