Copper-Catalyzed Single C-H Amination of 8-Aminoquinoline-Directed Ferrocenes.
Org Lett
; 23(13): 4966-4970, 2021 Jul 02.
Article
em En
| MEDLINE
| ID: mdl-34032452
ABSTRACT
An unprecedented copper-catalyzed C-H monoamination of ferrocenes directed by an 8-aminoquinoline amide directing group is described. This reaction proceeds in the presence of a catalytic amount of copper catalyst with both cyclic and acyclic amines to afford the various aminoferrocenes. The C-H amination of ortho-substituted ferroceneamides was also achieved, enabling rapid access to multisubstituted ferrocenes that are useful for developing new functional molecules.
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MEDLINE
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En
Ano de publicação:
2021
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Article