M2 macrophage accumulation contributes to pulmonary fibrosis, vascular dilatation, and hypoxemia in rat hepatopulmonary syndrome.

Chen, Bing; Yang, Yong; Yang, Congwen; Duan, Jiaxiang; Chen, Lin; Lu, Kaizhi; Yi, Bin; Chen, Yang; Xu, Duo; Huang, He

Chen, Bing; Yang, Yong; Yang, Congwen; Duan, Jiaxiang; Chen, Lin; Lu, Kaizhi; Yi, Bin; Chen, Yang; Xu, Duo; Huang, He.

Afiliação

Chen B; Department of Anesthesia, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yang Y; Department of Anesthesia, Southwest Hospital, Army Medical University (The Third Military Medical University), Chongqing, China.
Yang C; Department of Anesthesia, Southwest Hospital, Army Medical University (The Third Military Medical University), Chongqing, China.
Duan J; Department of Anesthesia, Southwest Hospital, Army Medical University (The Third Military Medical University), Chongqing, China.
Chen L; Department of Anesthesia, Southwest Hospital, Army Medical University (The Third Military Medical University), Chongqing, China.
Lu K; Department of Anesthesia, Southwest Hospital, Army Medical University (The Third Military Medical University), Chongqing, China.
Yi B; Department of Anesthesia, Southwest Hospital, Army Medical University (The Third Military Medical University), Chongqing, China.
Chen Y; Department of Anesthesia, Southwest Hospital, Army Medical University (The Third Military Medical University), Chongqing, China.
Xu D; Department of Anesthesia, Southwest Hospital, Army Medical University (The Third Military Medical University), Chongqing, China.
Huang H; Department of Anesthesia, Southwest Hospital, Army Medical University (The Third Military Medical University), Chongqing, China.

J Cell Physiol ; 236(11): 7682-7697, 2021 11.

Article em En | MEDLINE | ID: mdl-34041750

Assuntos

Síndrome Hepatopulmonar/etiologia; Hipóxia/etiologia; Pulmão/metabolismo; Macrófagos/metabolismo; Microvasos/metabolismo; Neutrófilos/metabolismo; Fibrose Pulmonar/etiologia; Animais; Compostos de Bifenilo/sangue; Movimento Celular; Proliferação de Células; Quimiocina CCL2/metabolismo; Dilatação Patológica; Fator Estimulador de Colônias de Granulócitos e Macrófagos/metabolismo; Síndrome Hepatopulmonar/imunologia; Síndrome Hepatopulmonar/metabolismo; Síndrome Hepatopulmonar/patologia; Hipóxia/imunologia; Hipóxia/metabolismo; Hipóxia/patologia; Mediadores da Inflamação/metabolismo; Leucina/análogos & derivados; Leucina/sangue; Cirrose Hepática Experimental/complicações; Pulmão/imunologia; Pulmão/patologia; Macrófagos/imunologia; Masculino; Microvasos/imunologia; Microvasos/patologia; Infiltração de Neutrófilos; Neutrófilos/imunologia; Fenótipo; Fibrose Pulmonar/imunologia; Fibrose Pulmonar/metabolismo; Fibrose Pulmonar/patologia; Ratos Sprague-Dawley; Receptores CCR2/metabolismo; Receptores de Fator Estimulador das Colônias de Granulócitos e Macrófagos/metabolismo; Fatores de Tempo; Fator de Crescimento Transformador beta1/metabolismo

Palavras-chave

fibrosis; granulocyte-macrophage colony stimulating factor; hepatopulmonary syndrome; macrophages; monocyte chemoattractant protein 1; neutrophils

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fibrose Pulmonar / Síndrome Hepatopulmonar / Microvasos / Pulmão / Macrófagos / Hipóxia / Neutrófilos Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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