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Structure-activity relationship and biological evaluation of berberine derivatives as PCSK9 down-regulating agents.
Fan, Tian-Yun; Yang, Yu-Xin; Zeng, Qing-Xuan; Wang, Xue-Lei; Wei, Wei; Guo, Xi-Xi; Zhao, Li-Ping; Song, Dan-Qing; Wang, Yan-Xiang; Wang, Li; Hong, Bin.
Afiliação
  • Fan TY; Institute of Medicinal Biotechnology, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 10050, China.
  • Yang YX; Institute of Medicinal Biotechnology, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 10050, China.
  • Zeng QX; Institute of Medicinal Biotechnology, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 10050, China.
  • Wang XL; Institute of Medicinal Biotechnology, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 10050, China.
  • Wei W; Institute of Medicinal Biotechnology, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 10050, China.
  • Guo XX; Institute of Medicinal Biotechnology, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 10050, China.
  • Zhao LP; Institute of Medicinal Biotechnology, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 10050, China.
  • Song DQ; Institute of Medicinal Biotechnology, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 10050, China.
  • Wang YX; Institute of Medicinal Biotechnology, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 10050, China. Electronic address: wangyanxiang@imb.pumc.edu.cn.
  • Wang L; Institute of Medicinal Biotechnology, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 10050, China. Electronic address: wangli_imb@163.com.
  • Hong B; Institute of Medicinal Biotechnology, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 10050, China. Electronic address: binhong69@hotmail.com.
Bioorg Chem ; 113: 104994, 2021 08.
Article em En | MEDLINE | ID: mdl-34052738
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Berberina / Regulação para Baixo / Inibidores Enzimáticos / Inibidores de PCSK9 Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Berberina / Regulação para Baixo / Inibidores Enzimáticos / Inibidores de PCSK9 Idioma: En Ano de publicação: 2021 Tipo de documento: Article