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Pharmacokinetic, pharmacodynamic, and immunogenic rationale for optimal dosing of pegvaliase, a PEGylated bacterial enzyme, in adult patients with phenylketonuria.
Qi, Yulan; Patel, Gina; Henshaw, Joshua; Gupta, Soumi; Olbertz, Joy; Larimore, Kevin; Harding, Cary O; Merilainen, Markus; Zori, Roberto; Longo, Nicola; Burton, Barbara K; Li, Mingjin; Gu, Zhonghua; Zoog, Stephen J; Weng, Haoling H; Schweighardt, Becky.
Afiliação
  • Qi Y; BioMarin Pharmaceutical Inc, Novato, CA, USA.
  • Patel G; BioMarin Pharmaceutical Inc, Novato, CA, USA.
  • Henshaw J; BioMarin Pharmaceutical Inc, Novato, CA, USA.
  • Gupta S; BioMarin Pharmaceutical Inc, Novato, CA, USA.
  • Olbertz J; BioMarin Pharmaceutical Inc, Novato, CA, USA.
  • Larimore K; BioMarin Pharmaceutical Inc, Novato, CA, USA.
  • Harding CO; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR, USA.
  • Merilainen M; BioMarin Pharmaceutical Inc, Novato, CA, USA.
  • Zori R; Division of Genetics and Metabolism, University of Florida, Gainesville, FL, USA.
  • Longo N; Division of Medical Genetics, University of Utah, Salt Lake City, UT, USA.
  • Burton BK; Division of Genetics, Birth Defects and Metabolism, Ann & Robert H. Lurie Children's Hospital, Chicago and Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Li M; BioMarin Pharmaceutical Inc, Novato, CA, USA.
  • Gu Z; BioMarin Pharmaceutical Inc, Novato, CA, USA.
  • Zoog SJ; BioMarin Pharmaceutical Inc, Novato, CA, USA.
  • Weng HH; BioMarin Pharmaceutical Inc, Novato, CA, USA.
  • Schweighardt B; BioMarin Pharmaceutical Inc, Novato, CA, USA.
Clin Transl Sci ; 14(5): 1894-1905, 2021 09.
Article em En | MEDLINE | ID: mdl-34057292
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenilalanina Amônia-Liase / Fenilcetonúrias / Hipersensibilidade a Drogas Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenilalanina Amônia-Liase / Fenilcetonúrias / Hipersensibilidade a Drogas Idioma: En Ano de publicação: 2021 Tipo de documento: Article