TLR7 Ligation Inhibits TLR8 Responsiveness in IL-27-Primed Human THP-1 Monocytes and Macrophages.

Odoardi, Natalya; Kourko, Olena; Petes, Carlene; Basta, Sameh; Gee, Katrina

Odoardi, Natalya; Kourko, Olena; Petes, Carlene; Basta, Sameh; Gee, Katrina.

Afiliação

Odoardi N; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
Kourko O; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
Petes C; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
Basta S; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
Gee K; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.

J Innate Immun ; 13(6): 345-358, 2021.

Article em En | MEDLINE | ID: mdl-34058746

Assuntos

Interleucina-27/imunologia; Macrófagos/imunologia; Monócitos/imunologia; Receptor 7 Toll-Like/imunologia; Receptor 8 Toll-Like/imunologia; Citocinas/imunologia; Humanos; Imunomodulação; Inflamação; RNA Mensageiro/metabolismo; Transdução de Sinais; Células THP-1; Receptor 7 Toll-Like/genética; Receptor 7 Toll-Like/metabolismo; Receptor 8 Toll-Like/genética; Receptor 8 Toll-Like/metabolismo

Palavras-chave

Inflammation; Interferon; Interleukin-27; Macrophages; Monocytes; Toll-like receptor; Toll-like receptor 7; Toll-like receptor 8

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Monócitos / Receptor 7 Toll-Like / Receptor 8 Toll-Like / Interleucina-27 / Macrófagos Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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