Vitamin D Deficiency in Testicular Cancer Survivors: A Systematic Review.
Int J Mol Sci
; 22(10)2021 May 13.
Article
em En
| MEDLINE
| ID: mdl-34067977
ABSTRACT
Testicular cancer (TC) is the most frequent tumor in young males. In the vast majority of cases, it is a curable disease; therefore, very often patients experience a long survival, also due to their young age at diagnosis. In the last decades, the role of the vitamin D deficiency related to orchiectomy has become an increasingly debated topic. Indeed, vitamin D is essential in bone metabolism and many other metabolic pathways, so its deficiency could lead to various metabolic disorders especially in long-term TC survivors. In our article, we report data from studies that evaluated the incidence of hypovitaminosis D in TC survivors compared with cohorts of healthy peers and we discuss molecular mechanisms and clinical implications.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Testiculares
/
Deficiência de Vitamina D
/
Sobreviventes de Câncer
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article