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Design and synthesis of 2-Substituted-4-benzyl-5-methylimidazoles as new potential Anti-breast cancer agents to inhibit oncogenic STAT3 functions.
Beshay, Botros Y; Abdellatef, Amira A; Loksha, Yasser M; Fahmy, Salwa M; Habib, Nargues S; Bekhit, Alaa El-Din A; Georghiou, Paris E; Hayakawa, Yoshihiro; Bekhit, Adnan A.
Afiliação
  • Beshay BY; Department of Pharmaceutical Chemistry, College of Pharmacy, Arab Academy for Science, Technology and Maritime Transport, Alexandria, Egypt.
  • Abdellatef AA; Section of Host Defences, Institute of Natural Medicine, University of Toyama, Toyama, Japan.
  • Loksha YM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sinai University, Al-Arish, North Sinai, Egypt.
  • Fahmy SM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, 2152 Alexandria, Egypt.
  • Habib NS; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, 2152 Alexandria, Egypt.
  • Bekhit AEA; Department of Food Science, University of Otago, Dunedin, New Zealand.
  • Georghiou PE; Department of Chemistry, Memorial University of Newfoundland, St. John's, NL, Canada.
  • Hayakawa Y; Section of Host Defences, Institute of Natural Medicine, University of Toyama, Toyama, Japan. Electronic address: haya@inm.u-toyama.ac.jp.
  • Bekhit AA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, 2152 Alexandria, Egypt; Pharmacy Program, Allied Health Department, College of Health and Sport Sciences, University of Bahrain, Bahrain; Cancer Nanotechnology Research Laboratory (CNRL), Faculty of Pharmacy, Alexand
Bioorg Chem ; 113: 105033, 2021 08.
Article em En | MEDLINE | ID: mdl-34089945
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Fator de Transcrição STAT3 / Imidazóis / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Fator de Transcrição STAT3 / Imidazóis / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article