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Design, synthesis, and biological evaluation of 2,4-diamino pyrimidine derivatives as potent FAK inhibitors with anti-cancer and anti-angiogenesis activities.
Wang, Shan; Zhang, Rong-Hong; Zhang, Hong; Wang, Yu-Chan; Yang, Dan; Zhao, Yong-Long; Yan, Guo-Yi; Xu, Guo-Bo; Guan, Huan-Yu; Zhou, Yan-Hua; Cui, Dong-Bing; Liu, Ting; Li, Yong-Jun; Liao, Shang-Gao; Zhou, Meng.
Afiliação
  • Wang S; State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang, 550004, PR China; School of Pharmacy, Guizhou Medical University, Guian New
  • Zhang RH; State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang, 550004, PR China; Center for Tissue Engineering and Stem Cell Research, Key
  • Zhang H; School of Pharmacy, Guizhou Medical University, Guian New District, Guizhou, PR China.
  • Wang YC; School of Pharmacy, Guizhou Medical University, Guian New District, Guizhou, PR China.
  • Yang D; School of Pharmacy, Guizhou Medical University, Guian New District, Guizhou, PR China.
  • Zhao YL; School of Pharmacy, Guizhou Medical University, Guian New District, Guizhou, PR China.
  • Yan GY; Department of Hepatobiliary Pancreatic Surgery, Henan Provincial People's Hospital, Henan University, Zhengzhou, PR China.
  • Xu GB; School of Pharmacy, Guizhou Medical University, Guian New District, Guizhou, PR China.
  • Guan HY; School of Pharmacy, Guizhou Medical University, Guian New District, Guizhou, PR China.
  • Zhou YH; Center for Tissue Engineering and Stem Cell Research, Key Laboratory of Regenerative Medicine of Guizhou Province, Guizhou Medical University, Guiyang, 550004, PR China.
  • Cui DB; Center for Tissue Engineering and Stem Cell Research, Key Laboratory of Regenerative Medicine of Guizhou Province, Guizhou Medical University, Guiyang, 550004, PR China.
  • Liu T; State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang, 550004, PR China; School of Pharmacy, Guizhou Medical University, Guian New
  • Li YJ; State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang, 550004, PR China; School of Pharmacy, Guizhou Medical University, Guian New
  • Liao SG; School of Pharmacy, Guizhou Medical University, Guian New District, Guizhou, PR China. Electronic address: lshangg@163.com.
  • Zhou M; State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guiyang, 550004, PR China; School of Pharmacy, Guizhou Medical University, Guian New
Eur J Med Chem ; 222: 113573, 2021 Oct 15.
Article em En | MEDLINE | ID: mdl-34091209
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Desenho de Fármacos / Inibidores da Angiogênese / Inibidores de Proteínas Quinases / Quinase 1 de Adesão Focal / Neovascularização Patológica / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Desenho de Fármacos / Inibidores da Angiogênese / Inibidores de Proteínas Quinases / Quinase 1 de Adesão Focal / Neovascularização Patológica / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article