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Synthesis and biological activity of conformationally restricted indole-based inhibitors of neurotropic alphavirus replication: Generation of a three-dimensional pharmacophore.
Barraza, Scott J; Sindac, Janice A; Dobry, Craig J; Delekta, Philip C; Lee, Pil H; Miller, David J; Larsen, Scott D.
Afiliação
  • Barraza SJ; Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, United States.
  • Sindac JA; Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, United States.
  • Dobry CJ; Departments of Internal Medicine and Microbiology and Immunology, University of Michigan, Ann Arbor, MI 48109, United States.
  • Delekta PC; Departments of Internal Medicine and Microbiology and Immunology, University of Michigan, Ann Arbor, MI 48109, United States.
  • Lee PH; Vahlteich Medicinal Chemistry Core, University of Michigan, Ann Arbor, MI 48109, United States; Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, United States.
  • Miller DJ; Departments of Internal Medicine and Microbiology and Immunology, University of Michigan, Ann Arbor, MI 48109, United States.
  • Larsen SD; Vahlteich Medicinal Chemistry Core, University of Michigan, Ann Arbor, MI 48109, United States; Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, United States. Electronic address: sdlarsen@med.umich.edu.
Bioorg Med Chem Lett ; 46: 128171, 2021 08 15.
Article em En | MEDLINE | ID: mdl-34098081
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Alphavirus / Indóis Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Alphavirus / Indóis Idioma: En Ano de publicação: 2021 Tipo de documento: Article