Comparative metabolomics and lipidomics study to evaluate the metabolic differences between first- and second-generation mammalian or mechanistic target of rapamycin inhibitors.

Rashid, Md Mamunur; Lee, Hyunbeom; Park, Jinyoung; Jung, Byung Hwa

Rashid, Md Mamunur; Lee, Hyunbeom; Park, Jinyoung; Jung, Byung Hwa.

Afiliação

Rashid MM; Molecular Recognition Research Center, Korea Institute of Science and Technology, Seoul, South Korea.
Lee H; Division of Bio-Medical Science and Technology, KIST School, Korea University of Science and Technology (UST), Seoul, South Korea.
Park J; Molecular Recognition Research Center, Korea Institute of Science and Technology, Seoul, South Korea.
Jung BH; Molecular Recognition Research Center, Korea Institute of Science and Technology, Seoul, South Korea.

Biomed Chromatogr ; 35(11): e5190, 2021 Nov.

Article em En | MEDLINE | ID: mdl-34101862

Assuntos

Lipidômica/métodos; Inibidores de MTOR/farmacologia; Metaboloma/efeitos dos fármacos; Metabolômica/métodos; Animais; Biomarcadores/sangue; Biomarcadores/urina; Cromatografia Líquida de Alta Pressão; Masculino; Espectrometria de Massas; Ratos; Ratos Sprague-Dawley

Palavras-chave

UHPLC-Orbitrap-MS; lipidomics; mTOR inhibitor; mammalian or mechanistic target of rapamycin, metabolomics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Metaboloma / Metabolômica / Lipidômica / Inibidores de MTOR Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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