Multidisciplinary treatment of primary intracranial yolk sac tumor: A case report and literature review.
Medicine (Baltimore)
; 100(19): e25778, 2021 May 14.
Article
em En
| MEDLINE
| ID: mdl-34106610
ABSTRACT
RATIONALE Intracranial yolk sac tumors (YSTs) are rare malignancies with limited treatment options and a dismal prognosis. They are usually managed with surgical resection and chemoradiotherapy. PATIENT CONCERNS Here, we report a patient with primary YST in the pineal region who achieved long term survival. Despite undergoing treatment, he experienced several recurrences over a 15-year period. DIAGNOSIS Brain magnetic resonance imaging (MRI) demonstrated the presence of space-occupying lesions in the pineal region and the medial tail of the left lateral ventricle. The tumors were excised, and the histological diagnosis suggested an intracranial YST. INTERVENTIONS:
The patient achieved long term survival after combined modality therapy including surgery, stereotactic radiosurgery (SRS)/intensity modulated radiation therapy (IMRT), chemotherapy, and targeted therapy.OUTCOMES:
The disease remained stable. However, the patient gave up treatment and passed away in October 2020, with a total survival of about 15âyears. LESSONS To the best of our knowledge, this patient with intracranial YST had received a longer survival compared with other published reports. We summarize previously published reports of intracranial YST and discuss the importance of multidisciplinary treatment. SRS may have a role, as a focal boost to residual tumor after resection or in case of recurrence after conventional radiotherapy, in the multimodality management of intracranial YSTs.
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Base de dados:
MEDLINE
Assunto principal:
Equipe de Assistência ao Paciente
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Glândula Pineal
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Neoplasias Encefálicas
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Tumor do Seio Endodérmico
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Ventrículos Laterais
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article