Influence of low-level-laser therapy on the stability of orthodontic mini-screw implants. A systematic review and meta-analysis.
Eur J Orthod
; 44(1): 11-21, 2022 01 25.
Article
em En
| MEDLINE
| ID: mdl-34114609
ABSTRACT
BACKGROUND:
The influence of low-level-laser therapy (LLLT) on the stability of orthodontic mini-screw implants (MSIs) has not been systematically reviewed.OBJECTIVES:
The aim was to assess the influence of LLLT on the stability of orthodontic MSIs.METHODS:
An unrestricted search of indexed databases was performed. SELECTION CRITERIA Randomized controlled clinical trials (RCTs) investigating the influence of LLLT on orthodontic MSI stability. DATA COLLECTION ANDANALYSIS:
Two authors independently performed study retrieval and selection, and data extraction. The risk of bias (RoB) of individual studies was assessed using the Cochrane RoB Tool for RCTs. Meta-analyses were performed separately for RCTs using periotest and resonance frequency analysis (RFA) to measure MSI stability; and a random effects model was applied. Subgroup analyses were performed based on the time-points of MSI stability evaluation. The quality of available evidence was evaluated using the Grades of Recommendation, Assessment, Development, and Evaluation approach.RESULTS:
Initially, 1332 articles were screened. Six RCTs with a split-mouth design were included. The periotest was used in 4 RCTs and 2 RCTs used RFA to measure MSI stability. All RCTs had a low RoB. Subgroup analyses based on periotest indicated that MSIs treated with LLLT had significantly higher stability than untreated MSIs at 21 and 30 days [weighted mean difference (MD) = -2.76, confidence interval (CI) [-4.17, -1.36], P-value = 0.0001) and at 60 days (weighted MD = -3.47, CI [-4.58, -2.36], P < 0.00001); and the level of certainty was high. Subgroup analyses based on RFA showed higher stability of MSIs treated with than without LLLT at 56 and 60 days (standardized MD = 0.82, CI [0.32, 1.32], P = 0.001), and at 70 and 90 days (standardized MD = 0.86, CI [0.36, 1.36], P = 0.0007); and the level of certainty was moderate.LIMITATIONS:
Due to limited number of relevant studies, it was not possible to perform sensitivity analysis, subgroup analyses for patient and intervention-related characteristics, and reporting biases assessment.CONCLUSIONS:
The role of LLLT on the secondary stability of MSIs placed in patients undergoing OT remains debatable. CLINICAL TRIAL REGISTRATION PROSPERO (CRD42021230291).
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Implantes Dentários
/
Terapia com Luz de Baixa Intensidade
/
Terapia a Laser
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article