Fanconi anemia proteins participate in a break-induced-replication-like pathway to counter replication stress.

Xu, Xinlin; Xu, Yixi; Guo, Ruiyuan; Xu, Ran; Fu, Congcong; Xing, Mengtan; Sasanuma, Hiroyuki; Li, Qing; Takata, Minoru; Takeda, Shunichi; Guo, Rong; Xu, Dongyi

Xu, Xinlin; Xu, Yixi; Guo, Ruiyuan; Xu, Ran; Fu, Congcong; Xing, Mengtan; Sasanuma, Hiroyuki; Li, Qing; Takata, Minoru; Takeda, Shunichi; Guo, Rong; Xu, Dongyi.

Afiliação

Xu X; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.
Xu Y; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China. xuyixi@westlake.edu.cn.
Guo R; School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China. xuyixi@westlake.edu.cn.
Xu R; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.
Fu C; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.
Xing M; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.
Sasanuma H; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.
Li Q; Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine, Shanghai East Hospital, School of Life Science and Technology, Shanghai Key Laboratory of Signaling and Disease Research, Tongji University, Shanghai, China.
Takata M; Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Takeda S; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.
Guo R; Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Radiation Biology Center, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
Xu D; Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Nat Struct Mol Biol ; 28(6): 487-500, 2021 06.

Article em En | MEDLINE | ID: mdl-34117478

Assuntos

Replicação do DNA; Proteínas de Grupos de Complementação da Anemia de Fanconi/fisiologia; Anemia de Fanconi/genética; Aneuploidia; Animais; Transtornos da Insuficiência da Medula Óssea/etiologia; Linhagem Celular Transformada; Galinhas; Quebra Cromossômica; Deleção Cromossômica; Cromossomos Humanos Par 7/genética; DNA Polimerase III/fisiologia; Replicação do DNA/genética; Progressão da Doença; Anemia de Fanconi/metabolismo; Proteínas de Grupos de Complementação da Anemia de Fanconi/deficiência; Proteínas de Grupos de Complementação da Anemia de Fanconi/genética; Feminino; Células HCT116; Células HEK293; Humanos; Hidroxiureia/farmacologia; Leucemia Mieloide Aguda/genética; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Modelos Genéticos; Especificidade da Espécie; Proteína 1 de Ligação à Proteína Supressora de Tumor p53/fisiologia; Ubiquitina-Proteína Ligases/fisiologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Replicação do DNA / Proteínas de Grupos de Complementação da Anemia de Fanconi / Anemia de Fanconi Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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