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FXa cleaves the SARS-CoV-2 spike protein and blocks cell entry to protect against infection with inferior effects in B.1.1.7 variant.
Dong, Wenjuan; Wang, Jing; Tian, Lei; Zhang, Jianying; Mead, Heather; Jaramillo, Sierra A; Li, Aimin; Zumwalt, Ross E; Whelan, Sean P J; Settles, Erik W; Keim, Paul S; Barker, Bridget Marie; Caligiuri, Michael A; Yu, Jianhua.
Afiliação
  • Dong W; Department of Hematology & Hematopoietic Cell Transplantation, City of Hope National Medical Center, Los Angeles, CA 91010, USA.
  • Wang J; Hematologic Malignancies Research Institute, City of Hope National Medical Center, Los Angeles, CA 91010, USA.
  • Tian L; Department of Hematology & Hematopoietic Cell Transplantation, City of Hope National Medical Center, Los Angeles, CA 91010, USA.
  • Zhang J; Hematologic Malignancies Research Institute, City of Hope National Medical Center, Los Angeles, CA 91010, USA.
  • Mead H; Department of Hematology & Hematopoietic Cell Transplantation, City of Hope National Medical Center, Los Angeles, CA 91010, USA.
  • Jaramillo SA; Hematologic Malignancies Research Institute, City of Hope National Medical Center, Los Angeles, CA 91010, USA.
  • Li A; Department of Computational and Quantitative Medicine, City of Hope National Medical Center, Los Angeles, CA 91010, USA.
  • Zumwalt RE; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, AZ 86011, USA.
  • Whelan SPJ; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, AZ 86011, USA.
  • Settles EW; Pathology Core of Shared Resources Core, Beckman Research Institute, City of Hope National Medical Center, Los Angeles, CA 91010, USA.
  • Keim PS; Department of Pathology, University of New Mexico, Albuquerque, NM 87131, USA.
  • Barker BM; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Caligiuri MA; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, AZ 86011, USA.
  • Yu J; Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, AZ 86011, USA.
bioRxiv ; 2021 Jun 08.
Article em En | MEDLINE | ID: mdl-34127969
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article