Analogs of the carotane antibiotic fulvoferruginin from submerged cultures of a Thai Marasmius sp.
Beilstein J Org Chem
; 17: 1385-1391, 2021.
Article
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| MEDLINE
| ID: mdl-34136017
ABSTRACT
A recent find of a Marasmius species in Northern Thailand led to the isolation of five unprecedented derivatives of the carotane antibiotic fulvoferruginin (1), fulvoferruginins B-F (2-6). The structures of these sesquiterpenoids were elucidated using HRESIMS, 1D and 2D NMR, as well as CD spectroscopy. Assessing the bioactivity, fulvoferruginin emerged as a potent cytotoxic agent of potential pharmaceutical interest.
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MEDLINE
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En
Ano de publicação:
2021
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Article