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RENEB/EURADOS field exercise 2019: robust dose estimation under outdoor conditions based on the dicentric chromosome assay.
Endesfelder, David; Oestreicher, Ursula; Kulka, Ulrike; Ainsbury, Elizabeth A; Moquet, Jayne; Barnard, Stephen; Gregoire, Eric; Martinez, Juan S; Trompier, François; Ristic, Yoann; Woda, Clemens; Waldner, Lovisa; Beinke, Christina; Vral, Anne; Barquinero, Joan-Francesc; Hernandez, Alfredo; Sommer, Sylwester; Lumniczky, Katalin; Hargitai, Rita; Montoro, Alegría; Milic, Mirta; Monteiro Gil, Octávia; Valente, Marco; Bobyk, Laure; Sevriukova, Olga; Sabatier, Laure; Prieto, María Jesús; Moreno Domene, Mercedes; Testa, Antonella; Patrono, Clarice; Terzoudi, Georgia; Triantopoulou, Sotiria; Histova, Rositsa; Wojcik, Andrzej.
Afiliação
  • Endesfelder D; Bundesamt für Strahlenschutz, BfS, Oberschleissheim, Germany.
  • Oestreicher U; Bundesamt für Strahlenschutz, BfS, Oberschleissheim, Germany.
  • Kulka U; Bundesamt für Strahlenschutz, BfS, Oberschleissheim, Germany.
  • Ainsbury EA; Public Health England, CRCE, Didcot, UK.
  • Moquet J; Public Health England, CRCE, Didcot, UK.
  • Barnard S; Public Health England, CRCE, Didcot, UK.
  • Gregoire E; Institut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, France.
  • Martinez JS; Institut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, France.
  • Trompier F; Institut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, France.
  • Ristic Y; Institut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, France.
  • Woda C; Helmholtz Zentrum München, Institute of Radiation Medicine, Neuherberg, Germany.
  • Waldner L; Department of Translational Medicine, Medical Radiation Physics, Lund University, Malmö, Sweden.
  • Beinke C; Bundeswehr Institute of Radiobiology, Munich, Germany.
  • Vral A; Faculty of Medicine and Health Sciences, Universiteit Gent, Gent, Belgium.
  • Barquinero JF; Department of Animal Biology, Plant Biology and Ecology, Universitat Autònoma de Barcelona, Bellaterra, Spain.
  • Hernandez A; Department of Animal Biology, Plant Biology and Ecology, Universitat Autònoma de Barcelona, Bellaterra, Spain.
  • Sommer S; Independent Researcher, London, UK.
  • Lumniczky K; Institut Chemii i Techniki Jadrowej, Warszawa, Poland.
  • Hargitai R; Department of Radiobiology and Radiohygiene, Unit of Radiation Medicine, National Public Health Centre, Budapest, Hungary.
  • Montoro A; Department of Radiobiology and Radiohygiene, Unit of Radiation Medicine, National Public Health Centre, Budapest, Hungary.
  • Milic M; Laboratorio de Dosimetría Biológica, Servicio de Protección Radiológica Hospital, Universitario Politécnico la Fe, Valencia, Spain.
  • Monteiro Gil O; Institute for Medical Research and Occupational Health Mutagenesis Unit, Zagreb, Croatia.
  • Valente M; Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal.
  • Bobyk L; Department of Radiation Biological, Armed Forces Biomedical Research Institute, Brétigny-sur-Orge, France.
  • Sevriukova O; Department of Radiation Biological, Armed Forces Biomedical Research Institute, Brétigny-sur-Orge, France.
  • Sabatier L; Department of Expertise and Exposure Monitoring, Radiation Protection Centre, Vilnius, Lithuania.
  • Prieto MJ; PROCyTOX, Commissariat à l'Energie Atomique et aux Energies Alternatives, Fontenay-aux-Roses, France.
  • Moreno Domene M; Graduate School Life Science and Health, Université Paris, Saclay, France.
  • Testa A; Laboratorio de Dosimetría Biológica, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
  • Patrono C; Laboratorio de Dosimetría Biológica, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
  • Terzoudi G; Agenzia Nazionale per le Nuove Tecnologie, L'energia e lo Sviluppo Economico Sostenibile, Rome, Italy.
  • Triantopoulou S; Agenzia Nazionale per le Nuove Tecnologie, L'energia e lo Sviluppo Economico Sostenibile, Rome, Italy.
  • Histova R; Health Physics, Radiobiology and Cytogenetics Laboratory, National Centre for Scientific Research 'Demokritos', Athens, Greece.
  • Wojcik A; Health Physics, Radiobiology and Cytogenetics Laboratory, National Centre for Scientific Research 'Demokritos', Athens, Greece.
Int J Radiat Biol ; 97(9): 1181-1198, 2021.
Article em En | MEDLINE | ID: mdl-34138666
ABSTRACT

PURPOSE:

Biological and/or physical assays for retrospective dosimetry are valuable tools to recover the exposure situation and to aid medical decision making. To further validate and improve such biological and physical assays, in 2019, EURADOS Working Group 10 and RENEB performed a field exercise in Lund, Sweden, to simulate various real-life exposure scenarios. MATERIALS AND

METHODS:

For the dicentric chromosome assay (DCA), blood tubes were located at anthropomorphic phantoms positioned in different geometries and were irradiated with a 1.36 TBq 192Ir-source. For each exposure condition, dose estimates were provided by at least one laboratory and for four conditions by 17 participating RENEB laboratories. Three radio-photoluminescence glass dosimeters were placed at each tube to assess reference doses.

RESULTS:

The DCA results were homogeneous between participants and matched well with the reference doses (≥95% of estimates within ±0.5 Gy of the reference). For samples close to the source systematic underestimation could be corrected by accounting for exposure time. Heterogeneity within and between tubes was detected for reference doses as well as for DCA doses estimates.

CONCLUSIONS:

The participants were able to successfully estimate the doses and to provide important information on the exposure scenarios under conditions closely resembling a real-life situation.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Radiometria / Cromossomos Humanos Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Radiometria / Cromossomos Humanos Idioma: En Ano de publicação: 2021 Tipo de documento: Article