Mineral Bone Disorders in Kidney Transplantation.
Semin Nephrol
; 41(2): 168-179, 2021 03.
Article
em En
| MEDLINE
| ID: mdl-34140095
ABSTRACT
Bone disease after kidney transplantation is associated with an increased risk of fractures, morbidity, and mortality. Its pathophysiology is complex, involving multiple contributors including pretransplant bone disease, immunosuppressive medications, and changes in the parathyroid-bone-kidney axis. Risk scores, bone turnover markers, and noninvasive imaging modalities are only able to partially predict the fracture risk in kidney transplant recipients. The optimal management of bone disease after kidney transplantation has not yet been established, with only a limited number of randomized clinical trials evaluating the efficacy of treatment regimens in kidney transplant recipients. This review focuses on the pathophysiology, evaluation, prevention, and treatment of post-kidney transplant mineral and bone disease as guided by recent evidence.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Ósseas
/
Transplante de Rim
/
Fraturas Ósseas
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article