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Plug and play with recombinant antibody fragments.
Grahn, Ashley K; Miller, Christina J; Kay, Brian K.
Afiliação
  • Grahn AK; Tango Biosciences, Chicago, IL 60612, USA.
  • Miller CJ; Tango Biosciences, Chicago, IL 60612, USA.
  • Kay BK; Tango Biosciences, Chicago, IL 60612, USA; University of Illinois at Chicago, Chicago, IL 60607, USA. Electronic address: bkay@uic.edu.
Cell Chem Biol ; 28(6): 745-747, 2021 06 17.
Article em En | MEDLINE | ID: mdl-34143957
ABSTRACT
In this issue of Cell Chemical Biology, Hentrich et al. (2021) describe the application of the SpyCatcher technology to antibody discovery and validation. Fab-SpyTag fusion proteins can be expressed in the periplasm of protease-deficient bacteria and coupled in a modular manner to a variety of SpyCatcher-tagged proteins for improved assay performance.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Imunoglobulinas Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Imunoglobulinas Idioma: En Ano de publicação: 2021 Tipo de documento: Article