Two new lanthanide complexes with 5-(Pyrazol-1-yl)nicotinic acid: Structures and their anti-cancer properties.

Zhu, Xiaopeng; Li, Zhipeng; Ji, Xiaoxi; Chen, Qing; Wu, Shuangyan; Gao, Enjun; Zhu, Mingchang

Zhu, Xiaopeng; Li, Zhipeng; Ji, Xiaoxi; Chen, Qing; Wu, Shuangyan; Gao, Enjun; Zhu, Mingchang.

Afiliação

Zhu X; International Key Laboratory of Liaoning Inorganic Molecule-Based Chemical and Department of Coordination Chemistry, Shenyang University of Chemical Technology, Shenyang 110142, PR China.
Li Z; International Key Laboratory of Liaoning Inorganic Molecule-Based Chemical and Department of Coordination Chemistry, Shenyang University of Chemical Technology, Shenyang 110142, PR China.
Ji X; International Key Laboratory of Liaoning Inorganic Molecule-Based Chemical and Department of Coordination Chemistry, Shenyang University of Chemical Technology, Shenyang 110142, PR China.
Chen Q; International Key Laboratory of Liaoning Inorganic Molecule-Based Chemical and Department of Coordination Chemistry, Shenyang University of Chemical Technology, Shenyang 110142, PR China.
Wu S; International Key Laboratory of Liaoning Inorganic Molecule-Based Chemical and Department of Coordination Chemistry, Shenyang University of Chemical Technology, Shenyang 110142, PR China.
Gao E; School of Chemical Engineering, University of Science and Technology Liaoning, Anshan 114051, PR China.
Zhu M; International Key Laboratory of Liaoning Inorganic Molecule-Based Chemical and Department of Coordination Chemistry, Shenyang University of Chemical Technology, Shenyang 110142, PR China; Key Laboratory of Resource Chemical Technology and Materials, (Ministry of Education), Shenyang University Chemi

J Inorg Biochem ; 222: 111505, 2021 09.

Article em En | MEDLINE | ID: mdl-34144467

Assuntos

Antineoplásicos/farmacologia; Complexos de Coordenação/farmacologia; Ácidos Nicotínicos/farmacologia; Pirazóis/farmacologia; Antineoplásicos/síntese química; Antineoplásicos/metabolismo; Apoptose/efeitos dos fármacos; Complexos de Coordenação/síntese química; Complexos de Coordenação/metabolismo; DNA/metabolismo; Ensaios de Seleção de Medicamentos Antitumorais; Células HeLa; Humanos; Simulação de Acoplamento Molecular; Estrutura Molecular; Ácidos Nicotínicos/síntese química; Ácidos Nicotínicos/metabolismo; Praseodímio/química; Pirazóis/síntese química; Pirazóis/metabolismo; Samário/química

Palavras-chave

AnnexinV-FITC/PI flow; Anti-cancer; Complexes; DNA binding; Lanthanides; MTT

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Complexos de Coordenação / Ácidos Nicotínicos / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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