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Design, synthesis and biological evaluation of dual Bcl-2/Mcl-1 inhibitors bearing 2-(1H-indol-4-yl)benzoic acid scaffold.
Niu, Qun; Deng, Hongguang; Zhang, Zhenwei; Xu, Qinhao; Luan, Shenglin; Huang, Min; Liu, Dan; Zhao, Linxiang.
Afiliação
  • Niu Q; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Deng H; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Zhang Z; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Xu Q; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Luan S; Shenzhen Bay Laboratory, Shenzhen, China.
  • Huang M; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Liu D; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Zhao L; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address: linxiang.zhao@vip.sina.com.
Bioorg Med Chem Lett ; 47: 128215, 2021 09 01.
Article em En | MEDLINE | ID: mdl-34153472
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Proteínas Proto-Oncogênicas c-bcl-2 / Proteína de Sequência 1 de Leucemia de Células Mieloides / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Proteínas Proto-Oncogênicas c-bcl-2 / Proteína de Sequência 1 de Leucemia de Células Mieloides / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article