A National Cancer Database analysis of the patterns of care for meningeal melanocytoma.
Future Oncol
; 17(24): 3243-3251, 2021 Aug.
Article
em En
| MEDLINE
| ID: mdl-34156284
ABSTRACT
Aim:
To evaluate demographics, treatment patterns, radiotherapy utilization and patient outcomes in meningeal melanocytomas. Materials &methods:
The National Cancer Database was queried for meningeal melanocytomas diagnosed in 2002-2016. The effects of demographic, clinical and treatment variables were determined via Kaplan-Meier log-rank and Cox regression analyses.Results:
The median and 5-year overall survival were 57.46 months and 48%, respectively. Patients earning ≥$48K showed improved survival (p = 0.0319). Radiotherapy and chemotherapy were utilized in 37.7 and 9% of patients, respectively.Conclusion:
Income significantly affected survival. Surgery remains the mainstay approach. Radiotherapy was delivered in more than one-third of patients but did not impact survival. However, further analyses were limited by poor treatment modality information in the database.
Lay abstract
Aim:
To assess the impact of demographic, clinical and treatment factors on survival in patients with meningeal melanocytomas. Materials &methods:
Biostatistical analyses were conducted on patients diagnosed with meningeal melanocytomas between 2002 and 2016 using data from the National Cancer Database.Results:
The median and 5-year survival rate were 57.46 months and 48%, respectively. Patients with incomes ≥$48K showed improved survival (p = 0.0319). Radiotherapy and chemotherapy were administered in 37.7 and 9% of patients, respectively.Conclusion:
Income was a critical factor in increasing patient survival. Surgery serves as the primary means for treatment, while radiotherapy and chemotherapy remain underutilized.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Fatores Socioeconômicos
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Disparidades em Assistência à Saúde
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Melanoma
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Neoplasias Meníngeas
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article