Partially Purified Leaf Fractions of Azadirachta indica Inhibit Trypanosome Alternative Oxidase and Exert Antitrypanosomal Effects on Trypanosoma congolense.

Tauheed, Abdullah M; Mamman, Mohammed; Ahmed, Abubakar; Suleiman, Mohammed M; Balogun, Emmanuel O

Tauheed, Abdullah M; Mamman, Mohammed; Ahmed, Abubakar; Suleiman, Mohammed M; Balogun, Emmanuel O.

Afiliação

Tauheed AM; Department of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria, Kaduna, Nigeria. mtauheed@abu.edu.ng.
Mamman M; Department of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria, Kaduna, Nigeria.
Ahmed A; Department of Pharmacognosy and Drug Development, Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Zaria, Kaduna, Nigeria.
Suleiman MM; Department of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria, Kaduna, Nigeria.
Balogun EO; Department of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University, Zaria, Kaduna, Nigeria.

Acta Parasitol ; 67(1): 120-129, 2022 Mar.

Article em En | MEDLINE | ID: mdl-34156634

Assuntos

Azadirachta; Trypanosoma congolense; Tripanossomíase Africana; Animais; Camundongos; Proteínas Mitocondriais; Oxirredutases; Folhas de Planta; Proteínas de Plantas; Ratos; Tripanossomíase Africana/tratamento farmacológico

Palavras-chave

Drug discovery; Ex vivo; In vitro; In vivo; Malondialdehyde; Trypanosome metabolism

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tripanossomíase Africana / Trypanosoma congolense / Azadirachta Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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