Neurological and gastrointestinal symptoms as an initial presentation of pediatric thyroid storm: report of three cases.
J Pediatr Endocrinol Metab
; 34(9): 1197-1200, 2021 Sep 27.
Article
em En
| MEDLINE
| ID: mdl-34162035
ABSTRACT
OBJECTIVES:
Thyroid storm (TS) is a rare but life-threatening condition caused by decompensated hyperthyroidism. There is no consensus on how to diagnose pediatric TS. We report three pediatric cases of TS presenting with central nervous system (CNS) and gastrointestinal (GI) symptoms as the initial presentation of Graves' disease. CASE PRESENTATION They were previously healthy adolescents without family history of thyroid disease. CNS symptoms varied from agitation to coma. GI symptoms included abdominal pain, vomiting, and diarrhea. Their laboratory studies revealed thyrotoxicosis and positive result of thyroid-stimulating antibody (TSAb). They were admitted to the intensive care unit (ICU) and received the combination of an antithyroid drug, Lugol's solution, a beta antagonist, and hydrocortisone. The most severe case was a 13 year-old Japanese girl who presented with loss of consciousness and hemodynamic shock. She died after 5 days of intensive treatment.CONCLUSIONS:
Pediatricians should consider TS in the differential diagnosis when a patient exhibits both CNS and GI symptoms.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Doenças da Glândula Tireoide
/
Imunoglobulinas Estimuladoras da Glândula Tireoide
/
Gastroenteropatias
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Doenças do Sistema Nervoso
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article