Glucagon regulates the stability of REV-ERB&#945; to modulate hepatic glucose production in a model of lung cancer-associated cachexia.

Verlande, Amandine; Chun, Sung Kook; Goodson, Maggie O; Fortin, Bridget M; Bae, Hosung; Jang, Cholsoon; Masri, Selma

Glucagon regulates the stability of REV-ERBα to modulate hepatic glucose production in a model of lung cancer-associated cachexia.

Verlande, Amandine; Chun, Sung Kook; Goodson, Maggie O; Fortin, Bridget M; Bae, Hosung; Jang, Cholsoon; Masri, Selma.

Afiliação

Verlande A; Department of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine (UCI), Irvine, CA 92697, USA.
Chun SK; Department of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine (UCI), Irvine, CA 92697, USA.
Goodson MO; Department of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine (UCI), Irvine, CA 92697, USA.
Fortin BM; Department of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine (UCI), Irvine, CA 92697, USA.
Bae H; Department of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine (UCI), Irvine, CA 92697, USA.
Jang C; Department of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine (UCI), Irvine, CA 92697, USA.
Masri S; Department of Biological Chemistry, Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California, Irvine (UCI), Irvine, CA 92697, USA. smasri@uci.edu.

Sci Adv ; 7(26)2021 06.

Article em En | MEDLINE | ID: mdl-34172439

Assuntos

Adenocarcinoma de Pulmão; Neoplasias Pulmonares; Adenocarcinoma de Pulmão/patologia; Animais; Caquexia/etiologia; Caquexia/metabolismo; Caquexia/patologia; Ritmo Circadiano/genética; Glucagon/metabolismo; Glucose/metabolismo; Fígado/metabolismo; Neoplasias Pulmonares/metabolismo; Camundongos; Membro 1 do Grupo D da Subfamília 1 de Receptores Nucleares/genética; Membro 1 do Grupo D da Subfamília 1 de Receptores Nucleares/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adenocarcinoma de Pulmão / Neoplasias Pulmonares Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adenocarcinoma de Pulmão / Neoplasias Pulmonares Idioma: En Ano de publicação: 2021 Tipo de documento: Article