Ossifying Fibroma of Non-odontogenic Origin: A Fibro-osseous Lesion in the Craniofacial Skeleton to be (Re-)considered.
Head Neck Pathol
; 16(1): 257-267, 2022 Mar.
Article
em En
| MEDLINE
| ID: mdl-34173971
In the cranio-facial skeleton, a heterogeneous group of well characterized fibro-osseous lesions can be distinguished. Whereas fibrous dysplasia can affect any skeletal bone, ossifying fibroma and cemento-osseous dysplasia exclusively develop in the cranio-facial region, with most subtypes restricted to the tooth bearing areas of the jaws. Herein we present a series of 20 fibro-osseous lesions that developed mostly in the frontal bone and in the mandible, presenting as expansile intramedullary tumors with a unique histologic appearance and an indolent clinical course. We provide evidence that these tumors are distinct from the categories included in the WHO classification and are therefore currently unclassifiable. The definition of cemento-ossifying fibroma as an odontogenic neoplasm developing only in close proximity to teeth should be re-considered and incorporate also extragnathic lesions as shown here.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cranianas
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Neoplasias de Tecidos Moles
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Cementoma
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Tumores Odontogênicos
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Fibroma Ossificante
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Displasia Fibrosa Óssea
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article