6-Hydroxydopamine disrupts cellular copper homeostasis in human neuroblastoma SH-SY5Y cells.

Kondo, Mao; Hara, Hirokazu; Kamijo, Fuka; Kamiya, Tetsuro; Adachi, Tetsuo

Kondo, Mao; Hara, Hirokazu; Kamijo, Fuka; Kamiya, Tetsuro; Adachi, Tetsuo.

Afiliação

Kondo M; Laboratory of Clinical Pharmaceutics, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu, 501-1196, Japan.
Hara H; Laboratory of Clinical Pharmaceutics, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu, 501-1196, Japan.
Kamijo F; Laboratory of Clinical Pharmaceutics, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu, 501-1196, Japan.
Kamiya T; Laboratory of Clinical Pharmaceutics, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu, 501-1196, Japan.
Adachi T; Laboratory of Clinical Pharmaceutics, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu, 501-1196, Japan.

Metallomics ; 13(7)2021 07 12.

Article em En | MEDLINE | ID: mdl-34185060

Assuntos

Proteínas de Transporte de Cobre/antagonistas & inibidores; ATPases Transportadoras de Cobre/antagonistas & inibidores; Cobre/metabolismo; Homeostase; Chaperonas Moleculares/antagonistas & inibidores; Neuroblastoma/patologia; Estresse Oxidativo; Oxidopamina/farmacologia; Adrenérgicos/farmacologia; Morte Celular; Humanos; Neuroblastoma/metabolismo; Espécies Reativas de Oxigênio/metabolismo; Células Tumorais Cultivadas

Palavras-chave

ATP7A; Atox1; copper; copper homeostasis; oxidative stress; protein degradation

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxidopamina / Estresse Oxidativo / Chaperonas Moleculares / Cobre / ATPases Transportadoras de Cobre / Proteínas de Transporte de Cobre / Homeostase / Neuroblastoma Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google