Clinical Multigene Testing for Prostate Cancer.
Urol Clin North Am
; 48(3): 297-309, 2021 Aug.
Article
em En
| MEDLINE
| ID: mdl-34210486
ABSTRACT
Germline genetic testing for prostate cancer (PC) is increasingly important as the clinical utility of germline variants in this patient population is understood better. To better characterize the clinical landscape of germline testing in PC, published clinical cohorts of PC who underwent clinical germline genetic analysis at point of care are reviewed. Limitations and heterogeneity of these cohorts are highlighted and pathogenic results with established or potential clinical utility in PC noted. The need for additional germline genetic studies is underscored, because the number of PC patients studied lags greatly behind the high prevalence of the disease.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Próstata
/
Testes Genéticos
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Predisposição Genética para Doença
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article