Glucocorticoid-induced dose-related and site-specific bone remodelling, microstructure, and mechanical changes in cancellous and cortical bones.

Chen, Yan; Zhong, Zhiguo; Chen, Wenshuang; Lv, Xiaohua; Luo, Shi-Ying

Chen, Yan; Zhong, Zhiguo; Chen, Wenshuang; Lv, Xiaohua; Luo, Shi-Ying.

Afiliação

Chen Y; Guangdong Key Laboratory for R&D of Natural Drug, Department of Pharmacology, Marine Biomedical Research Institute, Guangdong Medical University, Zhanjiang, China.
Zhong Z; Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Chen W; Guangdong Key Laboratory for R&D of Natural Drug, Department of Pharmacology, Marine Biomedical Research Institute, Guangdong Medical University, Zhanjiang, China.
Lv X; Guangdong Key Laboratory for R&D of Natural Drug, Department of Pharmacology, Marine Biomedical Research Institute, Guangdong Medical University, Zhanjiang, China.
Luo SY; Guangdong Key Laboratory for R&D of Natural Drug, Department of Pharmacology, Marine Biomedical Research Institute, Guangdong Medical University, Zhanjiang, China.

Clin Exp Pharmacol Physiol ; 48(10): 1421-1429, 2021 10.

Article em En | MEDLINE | ID: mdl-34214197

Assuntos

Densidade Óssea/efeitos dos fármacos; Remodelação Óssea/efeitos dos fármacos; Reabsorção Óssea/tratamento farmacológico; Osso Esponjoso/patologia; Osso Cortical/efeitos dos fármacos; Glucocorticoides/farmacologia; Animais; Reabsorção Óssea/patologia; Osso Esponjoso/efeitos dos fármacos; Feminino; Ratos; Ratos Sprague-Dawley

Palavras-chave

bone microstructure; bone remodelling; cancellous; cortical; dexamethasone; mechanics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Reabsorção Óssea / Densidade Óssea / Remodelação Óssea / Osso Esponjoso / Osso Cortical / Glucocorticoides Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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