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Rational design of phenyl thiophene (pyridine) derivatives that overcome P-glycoprotein mediated MDR in MCF-7/ADR cell.
Li, Ya-Sheng; Mao, Shen; Zhao, Dong-Sheng; Wang, Can-Can; Zu, Dan; Yang, Xi; Liu, Gui-Jun; Wang, Si-Jia; Zhang, Bo; Bao, Xiao-Ze; Ye, Xin-Yi; Wei, Bin; Cui, Zi-Ning; Chen, Jian-Wei; Wang, Hong.
Afiliação
  • Li YS; College of Pharmaceutical Science & Green Pharmaceutical Collaborative Innovation Center of Yangtze River Del-ta Region, Zhejiang University of Technology, Hangzhou 310014, China.
  • Mao S; College of Pharmaceutical Science & Green Pharmaceutical Collaborative Innovation Center of Yangtze River Del-ta Region, Zhejiang University of Technology, Hangzhou 310014, China.
  • Zhao DS; Department of Pharmacy, Quanzhou Medical College, Quanzhou 362100, China.
  • Wang CC; College of Pharmaceutical Science & Green Pharmaceutical Collaborative Innovation Center of Yangtze River Del-ta Region, Zhejiang University of Technology, Hangzhou 310014, China.
  • Zu D; College of Pharmaceutical Science & Green Pharmaceutical Collaborative Innovation Center of Yangtze River Del-ta Region, Zhejiang University of Technology, Hangzhou 310014, China.
  • Yang X; College of Pharmaceutical Science & Green Pharmaceutical Collaborative Innovation Center of Yangtze River Del-ta Region, Zhejiang University of Technology, Hangzhou 310014, China.
  • Liu GJ; College of Pharmaceutical Science & Green Pharmaceutical Collaborative Innovation Center of Yangtze River Del-ta Region, Zhejiang University of Technology, Hangzhou 310014, China.
  • Wang SJ; College of Pharmaceutical Science & Green Pharmaceutical Collaborative Innovation Center of Yangtze River Del-ta Region, Zhejiang University of Technology, Hangzhou 310014, China; Center for Human Nutrition, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA.
  • Zhang B; College of Pharmaceutical Science & Green Pharmaceutical Collaborative Innovation Center of Yangtze River Del-ta Region, Zhejiang University of Technology, Hangzhou 310014, China.
  • Bao XZ; College of Pharmaceutical Science & Green Pharmaceutical Collaborative Innovation Center of Yangtze River Del-ta Region, Zhejiang University of Technology, Hangzhou 310014, China.
  • Ye XY; College of Pharmaceutical Science & Green Pharmaceutical Collaborative Innovation Center of Yangtze River Del-ta Region, Zhejiang University of Technology, Hangzhou 310014, China.
  • Wei B; College of Pharmaceutical Science & Green Pharmaceutical Collaborative Innovation Center of Yangtze River Del-ta Region, Zhejiang University of Technology, Hangzhou 310014, China.
  • Cui ZN; State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Integrative Microbiology Research Centre, Guangdong Province Key Laboratory of Microbial Signals and Disease Control, South China Agricultural University, Guangzhou 510642, China; Guangdong Laboratory for Lingnan
  • Chen JW; College of Pharmaceutical Science & Green Pharmaceutical Collaborative Innovation Center of Yangtze River Del-ta Region, Zhejiang University of Technology, Hangzhou 310014, China. Electronic address: cjw983617@zjut.edu.cn.
  • Wang H; College of Pharmaceutical Science & Green Pharmaceutical Collaborative Innovation Center of Yangtze River Del-ta Region, Zhejiang University of Technology, Hangzhou 310014, China. Electronic address: hongw@zjut.edu.cn.
Bioorg Chem ; 114: 105075, 2021 09.
Article em En | MEDLINE | ID: mdl-34217975

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / Tiofenos / Desenho de Fármacos / Membro 1 da Subfamília B de Cassetes de Ligação de ATP / Resistencia a Medicamentos Antineoplásicos / Neoplasias Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piridinas / Tiofenos / Desenho de Fármacos / Membro 1 da Subfamília B de Cassetes de Ligação de ATP / Resistencia a Medicamentos Antineoplásicos / Neoplasias Idioma: En Ano de publicação: 2021 Tipo de documento: Article