A Case of Minocycline-induced Linear Morphea Reactivation.

ABSTRACT

Morphea is a localized form of scleroderma that presents with dermal thickening and fibrotic plaques in the absence of internal organ involvement. Like many autoimmune conditions, these plaques have many different phases, starting out as active, red plaques before later burning out, leaving white, fibrotic plaques behind. Many drugs have been shown to induce morphea, including bleomycin and bromocriptine. We present a case of minocycline-induced reactivation of previously burned out morphea plaques. Minocycline is an important drug in dermatology and the reporting of new adverse events is important so as to help clinicians better weigh the risks and benefits of the drug for specific populations.