Single-cell transcriptome analysis of the zebrafish embryonic trunk.
PLoS One
; 16(7): e0254024, 2021.
Article
em En
| MEDLINE
| ID: mdl-34234366
ABSTRACT
During embryonic development, cells differentiate into a variety of distinct cell types and subtypes with diverse transcriptional profiles. To date, transcriptomic signatures of different cell lineages that arise during development have been only partially characterized. Here we used single-cell RNA-seq to perform transcriptomic analysis of over 20,000 cells disaggregated from the trunk region of zebrafish embryos at the 30 hpf stage. Transcriptional signatures of 27 different cell types and subtypes were identified and annotated during this analysis. This dataset will be a useful resource for many researchers in the fields of developmental and cellular biology and facilitate the understanding of molecular mechanisms that regulate cell lineage choices during development.
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Base de dados:
MEDLINE
Assunto principal:
Peixe-Zebra
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Perfilação da Expressão Gênica
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Embrião não Mamífero
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Análise de Célula Única
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Tronco
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article