Comparative Proteomic Analysis Reveals Varying Impact on Immune Responses in Phorbol 12-Myristate-13-Acetate-Mediated THP-1 Monocyte-to-Macrophage Differentiation.

Pinto, Sneha M; Kim, Hera; Subbannayya, Yashwanth; Giambelluca, Miriam S; Bösl, Korbinian; Ryan, Liv; Sharma, Animesh; Kandasamy, Richard K

Pinto, Sneha M; Kim, Hera; Subbannayya, Yashwanth; Giambelluca, Miriam S; Bösl, Korbinian; Ryan, Liv; Sharma, Animesh; Kandasamy, Richard K.

Afiliação

Pinto SM; Centre of Molecular Inflammation Research (CEMIR), and Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, Trondheim, Norway.
Kim H; Center for Systems Biology and Molecular Medicine, Yenepoya (Deemed to be University), Mangalore, India.
Subbannayya Y; Centre of Molecular Inflammation Research (CEMIR), and Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, Trondheim, Norway.
Giambelluca MS; Centre of Molecular Inflammation Research (CEMIR), and Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, Trondheim, Norway.
Bösl K; Centre of Molecular Inflammation Research (CEMIR), and Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, Trondheim, Norway.
Ryan L; Centre of Molecular Inflammation Research (CEMIR), and Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, Trondheim, Norway.
Sharma A; Department of Infectious Diseases, Medical Clinic, St. Olavs Hospital, Trondheim, Norway.
Kandasamy RK; Centre of Molecular Inflammation Research (CEMIR), and Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, Trondheim, Norway.

Front Immunol ; 12: 679458, 2021.

Article em En | MEDLINE | ID: mdl-34234780

Assuntos

Imunidade; Macrófagos/metabolismo; Monócitos/metabolismo; Proteoma; Proteômica; Biomarcadores; Diferenciação Celular/imunologia; Membrana Celular; Biologia Computacional/métodos; Citocinas/metabolismo; Perfilação da Expressão Gênica; Humanos; Imunidade Inata; Mediadores da Inflamação/metabolismo; Macrófagos/imunologia; Monócitos/imunologia; Proteômica/métodos; Transdução de Sinais; Células THP-1; Acetato de Tetradecanoilforbol/imunologia; Transcriptoma

Palavras-chave

TLR signaling; differentiation; functional networks; innate immune signaling; macrophage; monocyte; pathways

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Monócitos / Proteoma / Proteômica / Imunidade / Macrófagos Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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