Particulate matter causes telomere shortening and increase in cellular senescence markers in human lung epithelial cells.

Chang-Chien, Ju; Huang, Jing-Long; Tsai, Hui-Ju; Wang, Shih-Ling; Kuo, Ming-Ling; Yao, Tsung-Chieh

Chang-Chien, Ju; Huang, Jing-Long; Tsai, Hui-Ju; Wang, Shih-Ling; Kuo, Ming-Ling; Yao, Tsung-Chieh.

Afiliação

Chang-Chien J; Division of Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital, 5 Fu-Hsin Street, Kweishan, Taoyuan 33305, Taiwan.
Huang JL; School of Medicine, Chang Gung University College of Medicine, Taoyuan, Taiwan; Department of Pediatrics, New Taipei Municipal TuCheng Hospital, New Taipei, Taiwan; Community Medicine Research Center, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan.
Tsai HJ; Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Wang SL; Division of Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital, 5 Fu-Hsin Street, Kweishan, Taoyuan 33305, Taiwan.
Kuo ML; Division of Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital, 5 Fu-Hsin Street, Kweishan, Taoyuan 33305, Taiwan; Department of Pediatrics, New Taipei Municipal TuCheng Hospital, New Taipei, Taiwan; Department of Microbiology and Immunology, Graduate Institute
Yao TC; Division of Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital, 5 Fu-Hsin Street, Kweishan, Taoyuan 33305, Taiwan; School of Medicine, Chang Gung University College of Medicine, Taoyuan, Taiwan; Community Medicine Research Center, Chang Gung Memorial Hospital a

Ecotoxicol Environ Saf ; 222: 112484, 2021 Oct 01.

Article em En | MEDLINE | ID: mdl-34237641

Assuntos

Material Particulado; Encurtamento do Telômero; Senescência Celular; Células Epiteliais/metabolismo; Humanos; Pulmão/metabolismo; Material Particulado/toxicidade; Telômero; Proteína Supressora de Tumor p53/genética

Palavras-chave

Cell cycle; Human lung epithelial cell; Particulate matter; Senescence; Telomere length

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Material Particulado / Encurtamento do Telômero Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Material Particulado / Encurtamento do Telômero Idioma: En Ano de publicação: 2021 Tipo de documento: Article