Organic Cation Transporters are Involved in Fluoxetine Transport Across the Blood-Brain Barrier <i>In Vivo</i> and <i>In Vitro</i>.

Wang, Min; Sun, Yingying; Hu, Bingying; He, Zhisheng; Chen, Shanshan; Qi, Dake; An, Hai; Wei, Yang

Organic Cation Transporters are Involved in Fluoxetine Transport Across the Blood-Brain Barrier In Vivo and In Vitro.

Wang, Min; Sun, Yingying; Hu, Bingying; He, Zhisheng; Chen, Shanshan; Qi, Dake; An, Hai; Wei, Yang.

Afiliação

Wang M; Zhejiang Key Laboratory of Neuropsychiatric Drug Research, Hangzhou Medical College, Zhejiang Academy of Medical Sciences, No. 182, Tianmu Shan Road, 310013 Hangzhou, China.
Sun Y; Zhejiang Key Laboratory of Neuropsychiatric Drug Research, Hangzhou Medical College, Zhejiang Academy of Medical Sciences, No. 182, Tianmu Shan Road, 310013 Hangzhou, China.
Hu B; Zhejiang Key Laboratory of Neuropsychiatric Drug Research, Hangzhou Medical College, Zhejiang Academy of Medical Sciences, No. 182, Tianmu Shan Road, 310013 Hangzhou, China.
He Z; Zhejiang Key Laboratory of Neuropsychiatric Drug Research, Hangzhou Medical College, Zhejiang Academy of Medical Sciences, No. 182, Tianmu Shan Road, 310013 Hangzhou, China.
Chen S; Zhejiang Key Laboratory of Neuropsychiatric Drug Research, Hangzhou Medical College, Zhejiang Academy of Medical Sciences, No. 182, Tianmu Shan Road, 310013 Hangzhou, China.
Qi D; Zhejiang Key Laboratory of Neuropsychiatric Drug Research, Hangzhou Medical College, Zhejiang Academy of Medical Sciences, No. 182, Tianmu Shan Road, 310013 Hangzhou, China.
An H; Zhejiang Key Laboratory of Neuropsychiatric Drug Research, Hangzhou Medical College, Zhejiang Academy of Medical Sciences, No. 182, Tianmu Shan Road, 310013 Hangzhou, China.
Wei Y; Zhejiang Key Laboratory of Neuropsychiatric Drug Research, Hangzhou Medical College, Zhejiang Academy of Medical Sciences, No. 182, Tianmu Shan Road, 310013 Hangzhou, China.

Curr Drug Deliv ; 19(4): 508-517, 2022.

Article em En | MEDLINE | ID: mdl-34238184

Assuntos

Barreira Hematoencefálica; Fluoxetina; Membro 2 da Subfamília G de Transportadores de Cassetes de Ligação de ATP/metabolismo; Animais; Transporte Biológico; Barreira Hematoencefálica/metabolismo; Cromatografia Líquida; Corticosterona/metabolismo; Corticosterona/farmacologia; Células Endoteliais/metabolismo; Fluoxetina/metabolismo; Fluoxetina/farmacologia; Humanos; Proteínas de Neoplasias/metabolismo; Proteínas de Neoplasias/farmacologia; Prazosina/metabolismo; Prazosina/farmacologia; Ratos; Espectrometria de Massas em Tandem

Palavras-chave

Fluoxetine; OCTs; amantadine; blood-brain barrier; hCMEC/D3; prazosin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Barreira Hematoencefálica / Fluoxetina Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Barreira Hematoencefálica / Fluoxetina Idioma: En Ano de publicação: 2022 Tipo de documento: Article