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Short tau inversion recovery (STIR) after intravenous contrast agent administration obscures bone marrow edema-like signal on forefoot MRI.
Fischer, Tim; Baz, Yassir El; Waelti, Stephan; Wildermuth, Simon; Leschka, Sebastian; Güsewell, Sabine; Dietrich, Tobias Johannes.
Afiliação
  • Fischer T; Division of Radiology and Nuclear Medicine, Kantonsspital St. Gallen, St. Gallen, Switzerland. tim.fischer@kssg.ch.
  • Baz YE; Faculty of Medicine, University of Zurich, Zurich, Switzerland. tim.fischer@kssg.ch.
  • Waelti S; Division of Radiology and Nuclear Medicine, Kantonsspital St. Gallen, St. Gallen, Switzerland.
  • Wildermuth S; Division of Radiology and Nuclear Medicine, Kantonsspital St. Gallen, St. Gallen, Switzerland.
  • Leschka S; Faculty of Medicine, University of Zurich, Zurich, Switzerland.
  • Güsewell S; Division of Radiology and Nuclear Medicine, Kantonsspital St. Gallen, St. Gallen, Switzerland.
  • Dietrich TJ; Faculty of Medicine, University of Zurich, Zurich, Switzerland.
Skeletal Radiol ; 51(3): 573-579, 2022 Mar.
Article em En | MEDLINE | ID: mdl-34255126
ABSTRACT

OBJECTIVE:

Short tau or short TI inversion recovery (STIR) MRI sequences are considered a robust fat suppression technique. However, STIR also suppresses signals from other tissues with similar T1 relaxation times. This study investigates the in vivo effect of intravenous gadolinium-based T1-shortening contrast agent on STIR signal. MATERIALS AND

METHODS:

Institutional board approval and informed consent was obtained. MRI examinations (1.5-T or 3-T) of 31 prospectively included patients were analyzed by two readers. Signal intensity of degenerative bone marrow edema-like signal at the Lisfranc joint on precontrast STIR images and on STIR images acquired after intravenous contrast agent administration (gadoteric acid, gadolinium 0.5 mmol/ml, 15 ml) was measured. The medial cuneiform bone without observable bone marrow edema-like signal was considered a healthy tissue and served as a reference. Relative changes in signal intensity between precontrast and postcontrast images were calculated for the two tissues. Wilcoxon signed-rank test served for statistical analyses.

RESULTS:

In bone marrow edema-like signal, both readers observed a median signal change of -35% (interquartile range (IQR) 24) and -34% (IQR 21), respectively, on postcontrast STIR images compared to precontrast STIR. In healthy tissue, the signal remained constant on postcontrast STIR images (median change -2%, IQR 15, and 0%, IQR 17) respectively. For both readers, postcontrast signal change in bone marrow edema-like signal differed from that in healthy tissue (p < 0.001).

CONCLUSION:

Intravenous gadolinium-based contrast agent causes a significant reduction of signal intensity in bone marrow edema-like signal on routine STIR images. Thus, pathological MRI findings may be obscured.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças da Medula Óssea / Meios de Contraste Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças da Medula Óssea / Meios de Contraste Idioma: En Ano de publicação: 2022 Tipo de documento: Article