Long-term survival in multiresistant metastatic choriocarcinoma after pembrolizumab treatment: A case report.
Gynecol Oncol Rep
; 37: 100817, 2021 Aug.
Article
em En
| MEDLINE
| ID: mdl-34258357
ABSTRACT
â¢Checkpoint inhibitor therapy affecting PD-L1 as treatment for advanced solid tumors.â¢Success in trial pembrolizumab therapy in multiresistant metastatic choriocarcinoma.â¢Long-term remission after pembrolizumab therapy in multiresistant choriocarcinoma.â¢Only six reported cases, one with comparable follow-up and outcome.
CPI, checkpoint inhibitor; CT, computed tomography; Choriocarcinoma; ECOG, Eastern Cooperative Oncology Group; ETT, epithelioid trophoblastic tumor; GTD, gestational trophoblastic disease; GTN; GTN, gestational trophoblastic neoplasia; PD-1/PDL-1, programmed cell death-1/ programmed cell death ligand-1; PSTT, placental site trophoblastic tumor; Pembrolizumab; WHO, Worl Health Organization; cMRI, cerebral magnetic resonance imaging; ß-HCG; ß-HCG, beta-human chorionic gonadotropin
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MEDLINE
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2021
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Article