Global prevalence of long-term neurodevelopmental impairment following extremely preterm birth: a systematic literature review.
J Int Med Res
; 49(7): 3000605211028026, 2021 Jul.
Article
em En
| MEDLINE
| ID: mdl-34284680
ABSTRACT
OBJECTIVE:
Neurodevelopmental impairment (NDI) is a major complication of extreme prematurity. This systematic review was conducted to summarize the worldwide long-term prevalence of NDI associated with extreme prematurity.METHODS:
Embase and MEDLINE databases were searched for epidemiologic and observational/real-world studies, published in English between 2011 and 2016, reporting long-term prevalence of NDI (occurring from 1 year) among extremely preterm infants born at gestational age (GA) ≤28 weeks.RESULTS:
Of 2406 articles identified through searches, 69 met the protocol NDI definition (24 North America, 25 Europe, 20 Rest of World). Prevalence of any severity NDI in North America was 8%-59% at 18 months to 2 years, and 11%-37% at 2-5 years; prevalence of moderate NDI in Europe was 10%-13% at 18 months to 2 years, 3% at 2-5 years, and 9%-19% at ≥5 years; prevalence of any NDI in Rest of World was 15%-61% at 18 months to 2 years, and 42% at 2-5 years (no North America/Rest of World studies reported any NDI at ≥5 years). A trend toward higher prevalence of NDI with lower GA at birth was observed.CONCLUSIONS:
Extreme prematurity has a significant long-term worldwide impact on neurodevelopmental outcomes.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Nascimento Prematuro
/
Lactente Extremamente Prematuro
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article