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Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury.
Tonnus, Wulf; Meyer, Claudia; Steinebach, Christian; Belavgeni, Alexia; von Mässenhausen, Anne; Gonzalez, Nadia Zamora; Maremonti, Francesca; Gembardt, Florian; Himmerkus, Nina; Latk, Markus; Locke, Sophie; Marschner, Julian; Li, Wenjun; Short, Spencer; Doll, Sebastian; Ingold, Irina; Proneth, Bettina; Daniel, Christoph; Kabgani, Nazanin; Kramann, Rafael; Motika, Stephen; Hergenrother, Paul J; Bornstein, Stefan R; Hugo, Christian; Becker, Jan Ulrich; Amann, Kerstin; Anders, Hans-Joachim; Kreisel, Daniel; Pratt, Derek; Gütschow, Michael; Conrad, Marcus; Linkermann, Andreas.
Afiliação
  • Tonnus W; Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.
  • Meyer C; Biotechnology Center, Technische Universität Dresden, Dresden, Germany.
  • Steinebach C; Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.
  • Belavgeni A; Biotechnology Center, Technische Universität Dresden, Dresden, Germany.
  • von Mässenhausen A; Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, Bonn, Germany.
  • Gonzalez NZ; Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.
  • Maremonti F; Biotechnology Center, Technische Universität Dresden, Dresden, Germany.
  • Gembardt F; Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.
  • Himmerkus N; Biotechnology Center, Technische Universität Dresden, Dresden, Germany.
  • Latk M; Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.
  • Locke S; Biotechnology Center, Technische Universität Dresden, Dresden, Germany.
  • Marschner J; Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.
  • Li W; Biotechnology Center, Technische Universität Dresden, Dresden, Germany.
  • Short S; Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.
  • Doll S; Institute of Physiology, Christian-Albrecht-University Kiel, Kiel, Germany.
  • Ingold I; Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.
  • Proneth B; Biotechnology Center, Technische Universität Dresden, Dresden, Germany.
  • Daniel C; Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.
  • Kabgani N; Biotechnology Center, Technische Universität Dresden, Dresden, Germany.
  • Kramann R; Division of Nephrology, Department of Medicine IV, University Hospital LMU Munich, Munich, Germany.
  • Motika S; Department of Surgery, Washington University, Saint Louis, MO, USA.
  • Hergenrother PJ; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON, Canada.
  • Bornstein SR; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
  • Hugo C; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
  • Becker JU; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
  • Amann K; Department of Nephropathology, Friedrich-Alexander University (FAU) Erlangen-Nürnberg, Erlangen, Germany.
  • Anders HJ; Clinic for Renal and Hypertensive Disorders, Rheumatological and Immunological Disease, University Hospital of the RWTH Aachen, Aachen, Germany.
  • Kreisel D; Clinic for Renal and Hypertensive Disorders, Rheumatological and Immunological Disease, University Hospital of the RWTH Aachen, Aachen, Germany.
  • Pratt D; Department of Internal Medicine, Nephrology and Transplantation, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Gütschow M; Department of Pathobiology, University of Illinois, Urbana, IL, USA.
  • Conrad M; Department of Pathobiology, University of Illinois, Urbana, IL, USA.
  • Linkermann A; Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.
Nat Commun ; 12(1): 4402, 2021 07 20.
Article em En | MEDLINE | ID: mdl-34285231

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Traumatismo por Reperfusão / Injúria Renal Aguda / Ferroptose / Túbulos Renais Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Traumatismo por Reperfusão / Injúria Renal Aguda / Ferroptose / Túbulos Renais Idioma: En Ano de publicação: 2021 Tipo de documento: Article