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Effects of Treatment of Coronavirus Disease 2019 With Convalescent Plasma in 25 B-Cell-Depleted Patients.
Gharbharan, Arvind; GeurtsvanKessel, Corine H; Jordans, Carlijn C E; Blaauw, Marc; van der Klift, Marjolein; Hassing, Robert-Jan; Smits-Zwinkels, Marijn; Meertens, Maaike; van den Hout, Ella C; de Man, Anne Marie; Hageman, Ilse; Bogers, Susanne; van der Schoot, C Ellen; Swaneveld, Francis; Anas, Adam A; Rokx, Casper; Rijnders, Bart J A.
Afiliação
  • Gharbharan A; Department of Internal Medicine, Section of Infectious Diseases and Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands.
  • GeurtsvanKessel CH; Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Jordans CCE; Department of Internal Medicine, Section of Infectious Diseases and Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands.
  • Blaauw M; Department of Internal Medicine, Elisabeth-Tweesteden Hospital, Tilburg, The Netherlands.
  • van der Klift M; Department of Internal Medicine, Amphia Hospital, Breda, The Netherlands.
  • Hassing RJ; Department of Internal Medicine, Rijnstate Hospital, Arnhem, The Netherlands.
  • Smits-Zwinkels M; Department of Pulmonary Medicine, ZorgSaam Hospital, Terneuzen, The Netherlands.
  • Meertens M; Department of Intensive Care Medicine, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
  • van den Hout EC; Department of Internal Medicine, Northwest Clinics, Alkmaar, The Netherlands.
  • de Man AM; Department of Internal Medicine, Elkerliek Ziekenhuis, Helmond, The Netherlands.
  • Hageman I; Department of Internal Medicine, Jeroen Bosch Hospital, den Bosch, The Netherlands.
  • Bogers S; Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands.
  • van der Schoot CE; Department of Experimental Immunohematology, Sanquin Research, Amsterdam, The Netherlands.
  • Swaneveld F; Unit of Transfusion Medicine, Sanquin Blood Supply, Amsterdam, The Netherlands.
  • Anas AA; Department of Internal Medicine, Section of Infectious Diseases and Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands.
  • Rokx C; Department of Internal Medicine, Section of Infectious Diseases and Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands.
  • Rijnders BJA; Department of Internal Medicine, Section of Infectious Diseases and Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands.
Clin Infect Dis ; 74(7): 1271-1274, 2022 04 09.
Article em En | MEDLINE | ID: mdl-34293119
ABSTRACT
Twenty-five B-cell-depleted patients (24 following anti-CD19/20 therapy) diagnosed with coronavirus disease 2019 had been symptomatic for a median of 26 days but remained antibody negative. All were treated with convalescent plasma with high neutralizing antibody titers. Twenty-one (84%) recovered, indicating the potential therapeutic effects of this therapy in this particular population.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: COVID-19 Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: COVID-19 Idioma: En Ano de publicação: 2022 Tipo de documento: Article