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Standard therapy of Mycobacterium avium complex pulmonary disease shows limited efficacy in an open source hollow fibre system that simulates human plasma and epithelial lining fluid pharmacokinetics.
Ruth, Mike Marvin; Raaijmakers, Jelmer; van den Hombergh, Erik; Aarnoutse, Rob; Svensson, Elin M; Susanto, Budi O; Simonsson, Ulrika S H; Wertheim, Heiman; Hoefsloot, Wouter; van Ingen, Jakko.
Afiliação
  • Ruth MM; Radboudumc Center for Infectious Diseases, Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: mike.ruth@radboudumc.nl.
  • Raaijmakers J; Radboudumc Center for Infectious Diseases, Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands.
  • van den Hombergh E; Department of Pharmacy, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Aarnoutse R; Department of Pharmacy, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Svensson EM; Radboudumc Center for Infectious Diseases, Department of Pharmacy, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Pharmacy, Uppsala University, Sweden.
  • Susanto BO; Department of Pharmaceutical Biosciences, Uppsala University, Sweden.
  • Simonsson USH; Department of Pharmaceutical Biosciences, Uppsala University, Sweden.
  • Wertheim H; Radboudumc Center for Infectious Diseases, Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Hoefsloot W; Radboudumc Center for Infectious Diseases, Department of Pulmonary Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.
  • van Ingen J; Radboudumc Center for Infectious Diseases, Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: jakko.vaningen@radboudumc.nl.
Clin Microbiol Infect ; 28(3): 448.e1-448.e7, 2022 Mar.
Article em En | MEDLINE | ID: mdl-34332109

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecção por Mycobacterium avium-intracellulare / Pneumopatias Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecção por Mycobacterium avium-intracellulare / Pneumopatias Idioma: En Ano de publicação: 2022 Tipo de documento: Article