Coagulation and wound repair during COVID-19.
J Heart Lung Transplant
; 40(10): 1076-1081, 2021 10.
Article
em En
| MEDLINE
| ID: mdl-34334300
ABSTRACT
While COVID-19 is best known as a respiratory infection, SARS-CoV-2 causes systemic disease manifestations including coagulopathies. Both dysregulated extracellular matrix remodeling pathways and circulating coagulation proteins are hallmarks of severe COVID-19 and often continue after the resolution of acute infection. Coagulation proteins have proven effective as biomarkers for severe disease and anticoagulants are a mainstay of COVID-19 therapeutics in hospitalized patients. While much knowledge has been gained about the role of clotting pathway activation in COVID-19, much remains to be elucidated in this complex network of signaling pathways.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Cicatrização
/
Transtornos da Coagulação Sanguínea
/
COVID-19
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article